CUREXA PRP

Leukocyte Rich or Leukocyte Poor?You Prepare the PRP to Suit Your Treatment Goal.

Name: Curexa PRP
Brand: CUREXA PRP

The CUREXA PRP system offers two different centrifugation protocols that let you manage the leukocyte concentration according to the needs of each case and the goal of the application.

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# Controlled PRP Preparation

Matched to Your Treatment Goal
Dual Protocol System

CUREXA PRP is a vacuum PRP tube system that allows different plasma components to be prepared according to the requirements of the case.

The Amber PRP protocol prepares leukocyte rich plasma, while the Pure PRP protocol prepares leukocyte poor plasma, helping you make a choice suited to your application goal.

The 1 ml sodium citrate contained in the 16 × 100 mm tubes and the centrifugation parameters determined by rotor type support a controlled, consistent plasma preparation process.

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# Product Advantages

Two Different Protocol Options

The system offers two separate centrifugation protocols that allow you to prepare leukocyte rich Amber PRP or leukocyte poor Pure PRP according to your application goal.

Management of Leukocyte Concentration

The Amber PRP and Pure PRP options help to manage the leukocyte content of the plasma in line with the requirements of the case.

Optimised Vacuum Tube Design

The 16 × 100 mm vacuum PRP tubes contain 1 ml sodium citrate to prevent the whole blood from clotting and are designed to be used with centrifuges that have suitable tube slots.

Centrifugation Parameters Specific to Rotor Type

With a fixed angle rotor centrifuge, 500 RCF is applied for 3 minutes for Pure PRP and 500 RCF for 6 minutes for Amber PRP; with a swing out rotor centrifuge, 1150 RCF is applied for 4 minutes for Pure PRP and 1150 RCF for 8 minutes for Amber PRP.

Preparing PRP Suited to the Treatment Goal

The platelet rich plasma obtained with CUREXA PRP is prepared to support cellular healing processes in bone and soft tissue through the growth factors it contains.

Controlled Plasma Collection

In the Pure PRP protocol, the plasma above the erythrocyte layer is collected, while in the Amber PRP protocol a 2 ml plasma portion is collected together with the buffy coat above the erythrocyte layer.

Medical Device and Quality Standards

CUREXA PRP is designed as a medical device and is offered in line with the CE and ISO 13485 quality standards stated in the product text.

Training and Professional Support

Regecorp provides professionals with information on product use, application techniques, administrative processes, regenerative medicine training, workshops and congress or trade fair events.

# Application Protocol

Clinical Application Protocol

* This section is intended for healthcare professionals.

The blood collection, centrifuge protocols and plasma harvesting steps for Curexa PRP; intended for the professional use of physicians and healthcare professionals. To view the detailed protocol, you must declare that you are a healthcare professional.

# For physicians only

Curexa PRP Application Protocol

Method of Use

The blood collection needle is inserted into the cleansed (venous) site on the patient’s arm from which blood is to be drawn.
The PRP tubes are vacuum tubes; once a sufficient amount of blood has been collected, the process stops automatically.
Both tubes are centrifuged (the physician selects the protocol). The tubes are placed opposite one another and balanced.

Centrifuge Protocols

Protocol	Fixed-angle rotor centrifuge	Swing-out rotor centrifuge
Pure PRP	500 RCF & 3 minutes	1150 RCF & 4 minutes
Amber PRP	500 RCF & 6 minutes	1150 RCF & 8 minutes

500 RCF = 2000 RPM, 1150 RCF = 2900 RPM.

Plasma Harvesting

The long needle is inserted into the PRP tube and the PRP is collected from above the red blood cell (RBC) layer.

Pure PRP: all of the plasma above the erythrocyte layer is collected (LP-PRP, leucocyte-poor).
Amber PRP: a 2 ml portion is collected together with the buffy coat above the erythrocyte layer (LR-PRP, leucocyte-rich).

According to the selected protocol, the PRP layer is collected and administered by injection.

Device Requirements

The blood collection needle or set must not be finer than 21G.
The PRP tubes measure 16 x 100 mm; the centrifuge buckets must be compatible with this.
For plasma harvesting, the long needle should be 88-90 mm, 18-19G; the syringe should have a minimum capacity of 4 ml and be luer-lock. The collection needle must not be used in the injection procedure.

For detailed clinical techniques and individualised planning, please contact our team.

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Leukocyte Rich or Leukocyte Poor?You Prepare the PRP to Suit Your Treatment Goal.